David de Gea was seen limping off the field while the rest of his team mates took part in the pre-match warm up. He appeared to go over on his ankle, before taking off his gloves, then walking to the dressing room.
With such a youthful side, with youngsters Donald Love and Paddy McNair playing at the back, the former making his first start for the club, United could do with the experience of De Gea more than ever.
Sergio Romero starts for United and the club now have no goalkeeper on the bench.
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