Sir Alex’s side were not at their best when getting knocked out of the Europa League in midweek, but you can’t help but feel that competition was a distraction for them.
They can now focus on winning the Premiership, and the stats suggest that they will prove too strong for Wanderers.
The home side have have won just one of their last 14 Premier League games (W1 D5 L8), a run which started with a 1-4 defeat to United.
They are languishing in 19th and already look doomed to go down.
By stark contrast United are sitting top of the pile and come into this on the back of wins over Norwich, Spurs and West Brom.
They have won seven of their last 8 matches and have a striker in Rooney who is banging them in for fun.
Wazza has scored seven in his last four PL matches and is understandably favourite to score first at 4 with Betfred. But a safer bet is surely to take the 1.73 on offer with Boylesports to score anytime.
If I was forced to take a punt on who will net first though my money would be on Ashley Young who has been in good form and looks value at 8.5 with bet365 and Betfred as many firms go two points shorter.
I think United will win this with plenty to spare and expect them to go for the jugular right from the off.
I can’t see Wolves being able to contain them in the first 45 minutes, and that makes the 1.83 with Paddy Power in the HT/FT market look a great punt.
I fancy United to win 4-0 or 50, and those scores can be backed at 17 and 34 respectively with Betfred.